In general all uranium mixtures (natural, exhausted, and enriched) have the same chemical effect on your body. Huge amounts of uranium can react with the tissues in your body and damage your kidneys. This radiation damage from exposure to high levels of natural or exhausted uranium is not known to cause cancer.
Humans and animals exposed to high levels of uranium do not have higher cancer rates. The Committee on the Biological Effects of Ionizing Radiation (BEIR IV) reported that consumption of food or drinking water that has normal amounts of uranium will most likely notcause cancer.

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